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Moxifloxacin-induced QT(c) interval prolongations in healthy male Japanese and Caucasian volunteers: a direct comparison in a thorough QT study
AIM: We investigated whether moxifloxacin-induced QT(c) prolongations in Japanese and Caucasian healthy male volunteers were significantly different. METHODS: A two period, randomized, crossover, ICH-E14-compliant thorough QT (TQT) study compared placebo-corrected changes in QT(c) interval from base...
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Publicado no: | Br J Clin Pharmacol |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley & Sons, Ltd
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4574830/ https://ncbi.nlm.nih.gov/pubmed/26011050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12684 |
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