Moxifloxacin-induced QT(c) interval prolongations in healthy male Japanese and Caucasian volunteers: a direct comparison in a thorough QT study

AIM: We investigated whether moxifloxacin-induced QT(c) prolongations in Japanese and Caucasian healthy male volunteers were significantly different. METHODS: A two period, randomized, crossover, ICH-E14-compliant thorough QT (TQT) study compared placebo-corrected changes in QT(c) interval from base...

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Bibliografiska uppgifter
I publikationen:Br J Clin Pharmacol
Huvudupphovsmän: Morganroth, Joel, Wang, Yaning, Thorn, Michael, Kumagai, Yuji, Harris, Stuart, Stockbridge, Norman, Kleiman, Robert, Shah, Rashmi
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons, Ltd 2015
Ämnen:
Clinical Trials
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574830/
https://ncbi.nlm.nih.gov/pubmed/26011050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12684
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