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Drug-induced QT interval prolongation: does ethnicity of the thorough QT study population matter?

Inter-ethnic differences in drug responses have been well documented. Drug-induced QT interval prolongation is a major safety concern and therefore, regulatory authorities recommend a clinical thorough QT study (TQT) to investigate new drugs for their QT-prolonging potential. A positive study, deter...

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Detalhes bibliográficos
Autor principal: Shah, Rashmi R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579250/
https://ncbi.nlm.nih.gov/pubmed/22882246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04415.x
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