Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria

BACKGROUND: The World Health Organization endorses the use of artemisinin-based combination therapy for treatment of acute uncomplicated falciparum malaria in the second and third trimesters of pregnancy. However, the effects of pregnancy on the pharmacokinetics of artemisinin derivatives, such as a...

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Detalhes bibliográficos
Main Authors: Morris, Carrie A, Onyamboko, Marie A, Capparelli, Edmund, Koch, Matthew A, Atibu, Joseph, Lokomba, Vicky, Douoguih, Macaya, Hemingway-Foday, Jennifer, Wesche, David, Ryder, Robert W, Bose, Carl, Wright, Linda, Tshefu, Antoinette K, Meshnick, Steven, Fleckenstein, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098207/
https://ncbi.nlm.nih.gov/pubmed/21548983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-114
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