Human β-Globin Locus Control Region HS5 Contains CTCF- and Developmental Stage-Dependent Enhancer-Blocking Activity in Erythroid Cells

The human β-globin locus contains five developmentally regulated β-type globin genes. All five genes depend on the locus control region (LCR), located at the 5′ end of the locus, for abundant globin gene transcription. The LCR is composed of five DNase I-hypersensitive sites (HSs), at least a subset...

Description complète

Détails bibliographiques

Publié dans:	Mol Cell Biol
Auteurs principaux:	Tanimoto, Keiji, Sugiura, Akiko, Omori, Akane, Felsenfeld, Gary, Douglas Engel, James, Fukamizu, Akiyoshi
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2003
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309639/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645507/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.24.8946-8952.2003
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!