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Erythroid overexpression of C/EBPγ in transgenic mice affects γ-globin expression and fetal liver erythropoiesis
The CCAAT boxes of the β-like globin genes interact with three proteins: NF-Y, GATA-1 and NFE-6. We demonstrate that NFE-6 contains C/EBPγ, and address its role in globin gene regulation by erythroid overexpression of C/EBPγ, and a dominant-negative form C/EBPγΔB, in mice. Elevated levels of C/EBPγ,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305797/ https://ncbi.nlm.nih.gov/pubmed/11060036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.21.5856 |
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