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New Synthetic Thrombin Inhibitors: Molecular Design and Experimental Verification
BACKGROUND: The development of new anticoagulants is an important goal for the improvement of thromboses treatments. OBJECTIVES: The design, synthesis and experimental testing of new safe and effective small molecule direct thrombin inhibitors for intravenous administration. METHODS: Computer-aided...
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| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3095642/ https://ncbi.nlm.nih.gov/pubmed/21603576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019969 |
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