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The modification of the thrombin generation test for the clinical assessment of dabigatran etexilate efficiency

A new oral anticoagulant, dabigatran etexilate (DE, a prodrug of direct thrombin inhibitor (DTI) dabigatran), has been used clinically to prevent thrombosis. The assessment of dabigatran efficiency is necessary in some clinical cases, such as renal insufficiency, risk of bleeding, and drug interacti...

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Vydáno v:Sci Rep
Hlavní autoři: Gribkova, Irina V., Lipets, Elena N., Rekhtina, Irina G., Bernakevich, Alex I., Ayusheev, Dorzho B., Ovsepyan, Ruzanna A., Ataullakhanov, Fazoil I., Sinauridze, Elena I.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932519/
https://ncbi.nlm.nih.gov/pubmed/27377013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29242
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