The modification of the thrombin generation test for the clinical assessment of dabigatran etexilate efficiency

A new oral anticoagulant, dabigatran etexilate (DE, a prodrug of direct thrombin inhibitor (DTI) dabigatran), has been used clinically to prevent thrombosis. The assessment of dabigatran efficiency is necessary in some clinical cases, such as renal insufficiency, risk of bleeding, and drug interacti...

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Publicado en:Sci Rep
Main Authors: Gribkova, Irina V., Lipets, Elena N., Rekhtina, Irina G., Bernakevich, Alex I., Ayusheev, Dorzho B., Ovsepyan, Ruzanna A., Ataullakhanov, Fazoil I., Sinauridze, Elena I.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932519/
https://ncbi.nlm.nih.gov/pubmed/27377013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29242
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