Application of Molecular Modeling to Development of New Factor Xa Inhibitors

In consequence of the key role of factor Xa in the clotting cascade and absence of its activity in the processes that do not affect coagulation, this protein is an attractive target for development of new blood coagulation inhibitors. Factor Xa is more effective and convenient target for creation of...

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Détails bibliographiques
Publié dans:Biomed Res Int
Auteurs principaux: Sulimov, Vladimir B., Gribkova, Irina V., Kochugaeva, Maria P., Katkova, Ekaterina V., Sulimov, Alexey V., Kutov, Danil C., Shikhaliev, Khidmet S., Medvedeva, Svetlana M., Krysin, Michael Yu., Sinauridze, Elena I., Ataullakhanov, Fazoil I.
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592935/
https://ncbi.nlm.nih.gov/pubmed/26484350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/120802
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