Application of Molecular Modeling to Development of New Factor Xa Inhibitors

In consequence of the key role of factor Xa in the clotting cascade and absence of its activity in the processes that do not affect coagulation, this protein is an attractive target for development of new blood coagulation inhibitors. Factor Xa is more effective and convenient target for creation of...

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Bibliographic Details
Published in:Biomed Res Int
Main Authors: Sulimov, Vladimir B., Gribkova, Irina V., Kochugaeva, Maria P., Katkova, Ekaterina V., Sulimov, Alexey V., Kutov, Danil C., Shikhaliev, Khidmet S., Medvedeva, Svetlana M., Krysin, Michael Yu., Sinauridze, Elena I., Ataullakhanov, Fazoil I.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592935/
https://ncbi.nlm.nih.gov/pubmed/26484350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/120802
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