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New Synthetic Thrombin Inhibitors: Molecular Design and Experimental Verification

BACKGROUND: The development of new anticoagulants is an important goal for the improvement of thromboses treatments. OBJECTIVES: The design, synthesis and experimental testing of new safe and effective small molecule direct thrombin inhibitors for intravenous administration. METHODS: Computer-aided...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Sinauridze, Elena I., Romanov, Alexey N., Gribkova, Irina V., Kondakova, Olga A., Surov, Stepan S., Gorbatenko, Aleksander S., Butylin, Andrey A., Monakov, Mikhail Yu., Bogolyubov, Alexey A., Kuznetsov, Yuryi V., Sulimov, Vladimir B., Ataullakhanov, Fazoyl I.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3095642/
https://ncbi.nlm.nih.gov/pubmed/21603576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019969
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