Sensitivity and Robustness of Spatially Dependent Thrombin Generation and Fibrin Clot Propagation

Blood coagulation is a delicately regulated space- and time-dependent process that leads to the formation of fibrin clots preventing blood loss upon vascular injury. The sensitivity of the coagulation network was previously investigated without accounting for transport processes. To investigate its...

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Bibliographische Detailangaben
Veröffentlicht in:Biophys J
Hauptverfasser: Kuprash, Anna D., Shibeko, Alexey M., Vijay, Ramya, Nair, Sukesh C., Srivastava, Alok, Ataullakhanov, Fazoil I., Panteleev, Mikhail A., Balandina, Anna N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2018
Schlagworte:
Systems Biophysics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301986/
https://ncbi.nlm.nih.gov/pubmed/30514632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.11.009
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