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Design and synthesis of polyacrylamide-based oligonucleotide supports for use in nucleic acid diagnostics.
Polyacrylamide supports, in a range of pore sizes, were investigated as nucleic acid affinity matrices for the detection of target DNA or RNA sequences using a sandwich hybridization format. Bromoacetyl and thiol oligonucleotide derivatives were covalently linked to sulfhydryl- and bromoacetyl-polya...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1993
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC309420/ https://ncbi.nlm.nih.gov/pubmed/7684127 |
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