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Design and synthesis of polyacrylamide-based oligonucleotide supports for use in nucleic acid diagnostics.

Polyacrylamide supports, in a range of pore sizes, were investigated as nucleic acid affinity matrices for the detection of target DNA or RNA sequences using a sandwich hybridization format. Bromoacetyl and thiol oligonucleotide derivatives were covalently linked to sulfhydryl- and bromoacetyl-polya...

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Bibliografiske detaljer
Main Authors: Fahy, E, Davis, G R, DiMichele, L J, Ghosh, S S
Format: Artigo
Sprog:Inglês
Udgivet: 1993
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC309420/
https://ncbi.nlm.nih.gov/pubmed/7684127
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