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Design and characterization of decoy oligonucleotides containing locked nucleic acids

Transfection of cis-element double-stranded oligonucleotides, referred to as decoy ODNs, has been reported to be a powerful tool that provides a new class of antigene strategies for gene therapy. However, one of the major limitations of the decoy approach is the rapid degradation of phosphodiester o...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Crinelli, Rita, Bianchi, Marzia, Gentilini, Lucia, Magnani, Mauro
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117200/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12034831/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.11.2435
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