Design and characterization of decoy oligonucleotides containing locked nucleic acids

Transfection of cis-element double-stranded oligonucleotides, referred to as decoy ODNs, has been reported to be a powerful tool that provides a new class of antigene strategies for gene therapy. However, one of the major limitations of the decoy approach is the rapid degradation of phosphodiester o...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Crinelli, Rita, Bianchi, Marzia, Gentilini, Lucia, Magnani, Mauro
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2002
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117200/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12034831/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.11.2435
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