Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design

Use of antisense oligonucleotides is a versatile strategy for achieving control of gene expression. Unfortunately, the interpretation of antisense-induced phenotypes is sometimes difficult, and chemical modifications that improve the potency and specificity of antisense action would be useful. The i...

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I whakaputaina i:	Nucleic Acids Res
Ngā kaituhi matua:	Braasch, Dwaine A., Liu, Yinghui, Corey, David R.
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Oxford University Press 2002
Ngā marau:	Articles
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137965/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12466540/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf651
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