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Design and characterization of decoy oligonucleotides containing locked nucleic acids

Transfection of cis-element double-stranded oligonucleotides, referred to as decoy ODNs, has been reported to be a powerful tool that provides a new class of antigene strategies for gene therapy. However, one of the major limitations of the decoy approach is the rapid degradation of phosphodiester o...

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Détails bibliographiques
Auteurs principaux: Crinelli, Rita, Bianchi, Marzia, Gentilini, Lucia, Magnani, Mauro
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC117200/
https://ncbi.nlm.nih.gov/pubmed/12034831
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