Rapamycin treatment augments both protein ubiquitination and Akt activation in pressure-overloaded rat myocardium

Ubiquitin-mediated protein degradation is necessary for both increased ventricular mass and survival signaling for compensated hypertrophy in pressure-overloaded (PO) myocardium. Another molecular keystone involved in the hypertrophic growth process is the mammalian target of rapamycin (mTOR), which...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Harston, Rebecca K., McKillop, John C., Moschella, Phillip C., Van Laer, An, Quinones, Lakeya S., Baicu, Catalin F., Balasubramanian, Sundaravadivel, Zile, Michael R., Kuppuswamy, Dhandapani
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Signaling and Stress Response
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094075/
https://ncbi.nlm.nih.gov/pubmed/21357504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00545.2010
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker