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Lack of β3 integrin signaling contributes to calpain-mediated myocardial cell loss in pressure-overloaded myocardium

Although cardiac hypertrophy initially ensues as a compensatory mechanism it often culminates in congestive heart failure. Based on our earlier studies that calpain and β3 integrin play cell death and survival roles, respectively during pressure-overload (PO) hypertrophy, we investigated if the loss...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Suryakumar, Geetha, Kasiganesan, Harinath, Balasubramanian, Sundaravadivel, Kuppuswamy, Dhandapani
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319054/
https://ncbi.nlm.nih.gov/pubmed/20224428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e3181d9f5d4
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