Non-Smad Transforming Growth Factor-β Signaling Regulated by Focal Adhesion Kinase Binding the p85 Subunit of Phosphatidylinositol 3-Kinase

TGF-β modulates numerous diverse cellular phenotypes including growth arrest in epithelial cells and proliferation in fibroblasts. Although the Smad pathway is fundamental for the majority of these responses, recent evidence indicates that non-Smad pathways may also have a critical role. Here we rep...

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Detalhes bibliográficos
Main Authors: Hong, Min, Wilkes, Mark C., Penheiter, Sumedha G., Gupta, Shiv K., Edens, Maryanne, Leof, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093859/
https://ncbi.nlm.nih.gov/pubmed/21454615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233676
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