Phosphatidylinositol 3-Kinase p85α Subunit-Dependent Interaction with BCR/ABL-Related Fusion Tyrosine Kinases: Molecular Mechanisms and Biological Consequences

The p85α subunit of phosphatidylinositol 3-kinase (PI-3k) forms a complex with a protein network associated with oncogenic fusion tyrosine kinases (FTKs) such as BCR/ABL, TEL/ABL, TEL/JAK2, TEL/PDGFβR, and NPM/ALK, resulting in constitutive activation of the p110 catalytic subunit of PI-3k. Introduc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ren, Shu-yue, Bolton, Elisabeth, Mohi, M. Golam, Morrione, Andrea, Neel, Benjamin G., Skorski, Tomasz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234343/
https://ncbi.nlm.nih.gov/pubmed/16135792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.18.8001-8008.2005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados