Non-Smad Transforming Growth Factor-β Signaling Regulated by Focal Adhesion Kinase Binding the p85 Subunit of Phosphatidylinositol 3-Kinase

TGF-β modulates numerous diverse cellular phenotypes including growth arrest in epithelial cells and proliferation in fibroblasts. Although the Smad pathway is fundamental for the majority of these responses, recent evidence indicates that non-Smad pathways may also have a critical role. Here we rep...

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Détails bibliographiques
Auteurs principaux: Hong, Min, Wilkes, Mark C., Penheiter, Sumedha G., Gupta, Shiv K., Edens, Maryanne, Leof, Edward B.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093859/
https://ncbi.nlm.nih.gov/pubmed/21454615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233676
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