Internalization-Dependent and -Independent Requirements for Transforming Growth Factor β Receptor Signaling via the Smad Pathway

Members of the transforming growth factor β (TGF-β) family of proteins signal through cell surface transmembrane serine/threonine protein kinases known as type I and type II receptors. The TGF-β signal is extended through phosphorylation of receptor-associated Smad proteins by the type I receptor. A...

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Main Authors: Penheiter, Sumedha G., Mitchell, Hugh, Garamszegi, Nandor, Edens, Maryanne, Doré, Jr., Jules J. E., Leof, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC133902/
https://ncbi.nlm.nih.gov/pubmed/12052882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4750-4759.2002
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