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Noxa/Bcl-2 Protein Interactions Contribute to Bortezomib Resistance in Human Lymphoid Cells

Previous studies have suggested that the BH3 domain of the proapoptotic Bcl-2 family member Noxa only interacts with the anti-apoptotic proteins Mcl-1 and A1 but not Bcl-2. In view of the similarity of the BH3 binding domains of these anti-apoptotic proteins as well as recent evidence that studies o...

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Hlavní autoři: Smith, Alyson J., Dai, Haiming, Correia, Cristina, Takahashi, Rie, Lee, Sun-Hee, Schmitz, Ingo, Kaufmann, Scott H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093844/
https://ncbi.nlm.nih.gov/pubmed/21454712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.189092
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