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Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer
Exposure of DNA to UV radiation causes covalent linkages between adjacent pyrimidines. The most common lesion found in DNA from these UV-induced linkages is the cis-syn cyclobutane pyrimidine dimer (CPD). Human DNA polymerase κ (Polκ), a member of the Y-family of DNA polymerases, is unable to insert...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093752/ https://ncbi.nlm.nih.gov/pubmed/21354175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.02.042 |
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