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Distinct mechanisms of cis-syn thymine dimer bypass by Dpo4 and DNA polymerase η
UV-light-induced cyclobutane pyrimidine dimers (CPDs) present a severe block to synthesis by replicative DNA polymerases (Pols), whereas Polη promotes proficient and error-free replication through CPDs. Although the archael Dpo4, which, like Polη, belongs to the Y family of DNA Pols, can also replic...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1194933/ https://ncbi.nlm.nih.gov/pubmed/16116089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504380102 |
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