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Distinct mechanisms of cis-syn thymine dimer bypass by Dpo4 and DNA polymerase η

UV-light-induced cyclobutane pyrimidine dimers (CPDs) present a severe block to synthesis by replicative DNA polymerases (Pols), whereas Polη promotes proficient and error-free replication through CPDs. Although the archael Dpo4, which, like Polη, belongs to the Y family of DNA Pols, can also replic...

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Detalhes bibliográficos
Main Authors: Johnson, Robert E., Prakash, Louise, Prakash, Satya
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1194933/
https://ncbi.nlm.nih.gov/pubmed/16116089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504380102
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