Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer

Exposure of DNA to UV radiation causes covalent linkages between adjacent pyrimidines. The most common lesion found in DNA from these UV-induced linkages is the cis-syn cyclobutane pyrimidine dimer (CPD). Human DNA polymerase κ (Polκ), a member of the Y-family of DNA polymerases, is unable to insert...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Carpio, Rodrigo Vasquez-Del, Silverstein, Timothy D., Lone, Samer, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093752/
https://ncbi.nlm.nih.gov/pubmed/21354175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.02.042
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires