Tissue Nonspecific Alkaline Phosphatase Is Activated via a Two-step Mechanism by Zinc Transport Complexes in the Early Secretory Pathway

A number of enzymes become functional by binding to zinc during their journey through the early secretory pathway. The zinc transporters (ZnTs) located there play important roles in this step. We have previously shown that two zinc transport complexes, ZnT5/ZnT6 heterodimers and ZnT7 homo-oligomers,...

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Bibliografische gegevens
Hoofdauteurs: Fukunaka, Ayako, Kurokawa, Yayoi, Teranishi, Fumie, Sekler, Israel, Oda, Kimimitsu, Ackland, M. Leigh, Faundez, Victor, Hiromura, Makoto, Masuda, Seiji, Nagao, Masaya, Enomoto, Shuichi, Kambe, Taiho
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2011
Onderwerpen:
Protein Structure and Folding
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091242/
https://ncbi.nlm.nih.gov/pubmed/21402707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.227173
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