Demonstration and Characterization of the Heterodimerization of ZnT5 and ZnT6 in the Early Secretory Pathway

The majority of CDF/ZnT zinc transporters form homo-oligomers. However, ZnT5, ZnT6, and their orthologues form hetero-oligomers in the early secretory pathway where they load zinc onto zinc-requiring enzymes and maintain secretory pathway functions. The details of this hetero-oligomerization remain...

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Hauptverfasser: Fukunaka, Ayako, Suzuki, Tomoyuki, Kurokawa, Yayoi, Yamazaki, Tomohiro, Fujiwara, Naoko, Ishihara, Kaori, Migaki, Hitoshi, Okumura, Katsuzumi, Masuda, Seiji, Yamaguchi-Iwai, Yuko, Nagao, Masaya, Kambe, Taiho
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Membrane Transport, Structure, Function, and Biogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781478/
https://ncbi.nlm.nih.gov/pubmed/19759014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026435
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