Dissecting the Process of Activation of Cancer-promoting Zinc-requiring Ectoenzymes by Zinc Metalation Mediated by ZNT Transporters

Zinc-requiring ectoenzymes, including both secreted and membrane-bound enzymes, are considered to capture zinc in their active site for their activation in the early secretory pathway. This idea has been confirmed by our studies conducted using tissue-nonspecific alkaline phosphatase (TNAP), which i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Tsuji, Tokuji, Kurokawa, Yayoi, Chiche, Johanna, Pouysségur, Jacques, Sato, Hiroshi, Fukuzawa, Hideya, Nagao, Masaya, Kambe, Taiho
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2017
Pynciau:
Membrane Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313090/
https://ncbi.nlm.nih.gov/pubmed/28028180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.763946
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