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Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury

Complement research experienced a renaissance with the discovery of a third activation route, the lectin pathway. We developed a unique model of total lectin pathway deficiency, a mouse strain lacking mannan-binding lectin-associated serine protease-2 (MASP-2), and analyzed the role of MASP-2 in two...

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Detaylı Bibliyografya
Asıl Yazarlar: Schwaeble, Wilhelm J., Lynch, Nicholas J., Clark, James E., Marber, Michael, Samani, Nilesh J., Ali, Youssif Mohammed, Dudler, Thomas, Parent, Brian, Lhotta, Karl, Wallis, Russell, Farrar, Conrad A., Sacks, Steven, Lee, Haekyung, Zhang, Ming, Iwaki, Daisuke, Takahashi, Minoru, Fujita, Teizo, Tedford, Clark E., Stover, Cordula M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088599/
https://ncbi.nlm.nih.gov/pubmed/21502512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101748108
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