Mannan-binding lectin-associated serine protease 2 is critical for the development of renal ischemia reperfusion injury and mediates tissue injury in the absence of complement C4

Mannan-binding lectin-associated serine protease 2 (MASP-2) has been described as the essential enzyme for the lectin pathway (LP) of complement activation. Since there is strong published evidence indicating that complement activation via the LP critically contributes to ischemia reperfusion (IR) i...

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Publicat a:FASEB J
Autors principals: Asgari, Elham, Farrar, Conrad A., Lynch, Nicholas, Ali, Youssif M., Roscher, Silke, Stover, Cordula, Zhou, Wuding, Schwaeble, Wilhelm J., Sacks, Steven H.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2014
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5184842/
https://ncbi.nlm.nih.gov/pubmed/24868011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-246306
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