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Which pathways trigger the role of complement in ischaemia/reperfusion injury?

Investigations into the role of complement in ischemia/reperfusion (I/R) injury have identified common effector mechanisms that depend on the production of C5a and C5b-9 through the cleavage of C3. These studies have also defined an important role for C3 synthesized within ischemic kidney. Less clea...

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Detalhes bibliográficos
Main Authors: Farrar, Conrad A., Asgari, Elham, Schwaeble, Wilhelm J., Sacks, Steven H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500775/
https://ncbi.nlm.nih.gov/pubmed/23181062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00341
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