The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection

The complement system plays a key role in host defense against pneumococcal infection. Three different pathways, the classical, alternative and lectin pathways, mediate complement activation. While there is limited information available on the roles of the classical and the alternative activation pa...

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Detalhes bibliográficos
Main Authors: Ali, Youssif M., Lynch, Nicholas J., Haleem, Kashif S., Fujita, Teizo, Endo, Yuichi, Hansen, Soren, Holmskov, Uffe, Takahashi, Kazue, Stahl, Gregory L., Dudler, Thomas, Girija, Umakhanth V., Wallis, Russell, Kadioglu, Aras, Stover, Cordula M., Andrew, Peter W., Schwaeble, Wilhelm J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390405/
https://ncbi.nlm.nih.gov/pubmed/22792067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002793
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