CMX001 (1-O-Hexadecyloxypropyl-Cidofovir) Inhibits Polyomavirus JC Replication in Human Brain Progenitor-Derived Astrocytes

Polyomavirus JC (JCV) replication causes progressive multifocal leukoencephalopathy (PML), a frequently fatal brain disease in immunodeficient patients, yet antiviral drugs are lacking. We characterized the lipid conjugate 1-O-hexadecyloxypropyl-cidofovir (CMX001) regarding JCV (Mad-4) replication i...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Gosert, Rainer, Rinaldo, Christine Hanssen, Wernli, Marion, Major, Eugene O., Hirsch, Hans H.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088264/
https://ncbi.nlm.nih.gov/pubmed/21402853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00046-11
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires