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Brincidofovir (CMX001) Inhibits BK Polyomavirus Replication in Primary Human Urothelial Cells

BK polyomavirus (BKPyV)-associated hemorrhagic cystitis (PyVHC) complicates 5 to 15% of allogeneic hematopoietic stem cell transplantations. Targeted antivirals are still unavailable. Brincidofovir (BCV; previously CMX001) has shown inhibitory activity against diverse viruses, including BKPyV in a p...

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發表在:Antimicrob Agents Chemother
Main Authors: Tylden, Garth D., Hirsch, Hans H., Rinaldo, Christine Hanssen
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432119/
https://ncbi.nlm.nih.gov/pubmed/25801568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00238-15
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