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Antiviral Effects of Artesunate on Polyomavirus BK Replication in Primary Human Kidney Cells

Polyomavirus BK (BKV) causes polyomavirus-associated nephropathy (PyVAN) and hemorrhagic cystitis (PyVHC) in renal and bone marrow transplant patients, respectively. Antiviral drugs with targeted activity against BKV are lacking. Since the antimalarial drug artesunate was recently demonstrated to ha...

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Hlavní autoři: Sharma, Biswa Nath, Marschall, Manfred, Henriksen, Stian, Rinaldo, Christine Hanssen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910759/
https://ncbi.nlm.nih.gov/pubmed/24145549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01800-13
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