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1-O-Hexadecyloxypropyl Cidofovir (CMX001) Effectively Inhibits Polyomavirus BK Replication in Primary Human Renal Tubular Epithelial Cells

Antiviral drugs for treating polyomavirus BK (BKV) replication in polyomavirus-associated nephropathy or hemorrhagic cystitis are of considerable clinical interest. Unlike cidofovir, the lipid conjugate 1-O-hexadecyloxypropyl cidofovir (CMX001) is orally available and has not caused detectable nephr...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Rinaldo, Christine Hanssen, Gosert, Rainer, Bernhoff, Eva, Finstad, Solrun, Hirsch, Hans H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976161/
https://ncbi.nlm.nih.gov/pubmed/20713664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00974-10
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