Ether Lipid Ester Derivatives of Cidofovir Inhibit Polyomavirus BK Replication In Vitro

Polyomavirus BK is a significant pathogen in transplant recipients, but no effective antiviral therapy is available. We show that cidofovir can inhibit BK virus replication in vitro. Esterification of cidofovir with hexadecyloxypropyl, octadecyloxyethyl, and oleyloxyethyl groups results in up to a 3...

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Bibliografiske detaljer
Main Authors: Randhawa, Parmjeet, Farasati, Noush Afarin, Shapiro, Ron, Hostetler, Karl Y.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426942/
https://ncbi.nlm.nih.gov/pubmed/16569886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1564-1566.2006
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