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Ether Lipid Ester Derivatives of Cidofovir Inhibit Polyomavirus BK Replication In Vitro

Polyomavirus BK is a significant pathogen in transplant recipients, but no effective antiviral therapy is available. We show that cidofovir can inhibit BK virus replication in vitro. Esterification of cidofovir with hexadecyloxypropyl, octadecyloxyethyl, and oleyloxyethyl groups results in up to a 3...

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Détails bibliographiques
Auteurs principaux: Randhawa, Parmjeet, Farasati, Noush Afarin, Shapiro, Ron, Hostetler, Karl Y.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426942/
https://ncbi.nlm.nih.gov/pubmed/16569886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1564-1566.2006
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