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Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model

Adenoviruses (Ads) cause a wide array of end-organ and disseminated diseases in severely immunosuppressed patients. For example, ≈20% of pediatric allogeneic hematopoietic stem cell transplant recipients develop disseminated Ad infection, and the disease proves fatal in as many as 50–80% of these pa...

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Detalhes bibliográficos
Main Authors: Toth, Karoly, Spencer, Jacqueline F., Dhar, Debanjan, Sagartz, John E., Buller, R. Mark L., Painter, George R., Wold, William S. M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438243/
https://ncbi.nlm.nih.gov/pubmed/18490659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800200105
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