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Hexadecyloxypropyl-Cidofovir (CMX001) Suppresses JC Virus Replication in Human Fetal Brain SVG Cell Cultures

JC virus (JCV) is a polyomavirus that infects human oligodendrocytes, leading to development of progressive multifocal leukoencephalopathy (PML), an often fatal demyelinating disease occurring in immunocompromised individuals. Currently there are no effective therapies for the treatment of PML that...

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Detalhes bibliográficos
Main Authors: Jiang, Zhi-Gang, Cohen, Jeffrey, Marshall, Leslie J., Major, Eugene O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976159/
https://ncbi.nlm.nih.gov/pubmed/20823288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00837-10
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