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Hexadecyloxypropyl-Cidofovir (CMX001) Suppresses JC Virus Replication in Human Fetal Brain SVG Cell Cultures

JC virus (JCV) is a polyomavirus that infects human oligodendrocytes, leading to development of progressive multifocal leukoencephalopathy (PML), an often fatal demyelinating disease occurring in immunocompromised individuals. Currently there are no effective therapies for the treatment of PML that...

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Autors principals: Jiang, Zhi-Gang, Cohen, Jeffrey, Marshall, Leslie J., Major, Eugene O.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976159/
https://ncbi.nlm.nih.gov/pubmed/20823288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00837-10
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