Molecular Regulation of JC Virus Tropism: Insights into Potential Therapeutic Targets for Progressive Multifocal Leukoencephalopathy

por Marshall, Leslie J., Major, Eugene O.
Publicado 2010

Transcription factor Spi-B binds unique sequences present in the tandem repeat promoter/enhancer of JC virus and supports viral activity

por Marshall, Leslie J., Dunham, Lisa, Major, Eugene O.
Publicado 2010

Hexadecyloxypropyl-Cidofovir (CMX001) Suppresses JC Virus Replication in Human Fetal Brain SVG Cell Cultures

por Jiang, Zhi-Gang, Cohen, Jeffrey, Marshall, Leslie J., Major, Eugene O.
Publicado 2010

JC virus promoter/enhancers contain TATA box-associated Spi-B-binding sites that support early viral gene expression in primary astrocytes

por Marshall, Leslie J., Moore, Lisa D., Mirsky, Matthew M., Major, Eugene O.
Publicado 2012

RUNX1 Permits E4orf6-Directed Nuclear Localization of the Adenovirus E1B-55K Protein and Associates with Centers of Viral DNA and RNA Synthesis

por Marshall, Leslie J., Moore, Amy C., Ohki, Misao, Kitabayashi, Issay, Patterson, David, Ornelles, David A.
Publicado 2008

Differentiation of Human Fetal Multipotential Neural Progenitor Cells to Astrocytes Reveals Susceptibility Factors for JC Virus

por Ferenczy, Michael W., Johnson, Kory R., Marshall, Leslie J., Monaco, Maria Chiara, Major, Eugene O.
Publicado 2013

Lymphocyte Gene Expression and JC Virus Noncoding Control Region Sequences Are Linked with the Risk of Progressive Multifocal Leukoencephalopathy

por Marshall, Leslie J., Ferenczy, Michael W., Daley, Elizabeth L., Jensen, Peter N., Ryschkewitsch, Caroline F., Major, Eugene O.
Publicado 2014

Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain

por Ferenczy, Michael W., Marshall, Leslie J., Nelson, Christian D. S., Atwood, Walter J., Nath, Avindra, Khalili, Kamel, Major, Eugene O.
Publicado 2012

Human Obesity Associated with an Intronic SNP in the Brain-Derived Neurotrophic Factor Locus

por Mou, Zongyang, Hyde, Thomas M., Lipska, Barbara K., Martinowich, Keri, Wei, Peter, Ong, Chiew-Jen, Hunter, Lindsay A., Palaguachi, Gladys I., Morgun, Eva, Teng, Rujia, Lai, Chen, Condarco, Tania A., Demidowich, Andrew P., Krause, Amanda J., Marshall, Leslie J., Haack, Karin, Voruganti, V. Saroja, Cole, Shelley A., Butte, Nancy F., Comuzzie, Anthony G., Nalls, Michael A., Zonderman, Alan B., Singleton, Andrew B., Evans, Michele K., Martin, Bronwen, Maudsley, Stuart, Tsao, Jack W., Kleinman, Joel E., Yanovski, Jack A., Han, Joan C.
Publicado en Cell Rep (2015)