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Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain

Summary: Progressive multifocal leukoencephalopathy (PML) is a debilitating and frequently fatal central nervous system (CNS) demyelinating disease caused by JC virus (JCV), for which there is currently no effective treatment. Lytic infection of oligodendrocytes in the brain leads to their eventual...

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Detalhes bibliográficos
Main Authors: Ferenczy, Michael W., Marshall, Leslie J., Nelson, Christian D. S., Atwood, Walter J., Nath, Avindra, Khalili, Kamel, Major, Eugene O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416490/
https://ncbi.nlm.nih.gov/pubmed/22763635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CMR.05031-11
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