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Molecular Biology, Epidemiology, and Pathogenesis of Progressive Multifocal Leukoencephalopathy, the JC Virus-Induced Demyelinating Disease of the Human Brain

Summary: Progressive multifocal leukoencephalopathy (PML) is a debilitating and frequently fatal central nervous system (CNS) demyelinating disease caused by JC virus (JCV), for which there is currently no effective treatment. Lytic infection of oligodendrocytes in the brain leads to their eventual...

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Библиографические подробности
Главные авторы: Ferenczy, Michael W., Marshall, Leslie J., Nelson, Christian D. S., Atwood, Walter J., Nath, Avindra, Khalili, Kamel, Major, Eugene O.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416490/
https://ncbi.nlm.nih.gov/pubmed/22763635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CMR.05031-11
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