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Antiviral Effects of Artesunate on Polyomavirus BK Replication in Primary Human Kidney Cells

Polyomavirus BK (BKV) causes polyomavirus-associated nephropathy (PyVAN) and hemorrhagic cystitis (PyVHC) in renal and bone marrow transplant patients, respectively. Antiviral drugs with targeted activity against BKV are lacking. Since the antimalarial drug artesunate was recently demonstrated to ha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sharma, Biswa Nath, Marschall, Manfred, Henriksen, Stian, Rinaldo, Christine Hanssen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910759/
https://ncbi.nlm.nih.gov/pubmed/24145549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01800-13
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