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Ordered and Dynamic Assembly of Single Spliceosomes
The spliceosome is the complex macromolecular machine responsible for removing introns from precursors to mRNAs (pre-mRNAs). We combined yeast genetic engineering, chemical biology, and multi-wavelength fluoresence microscopy to follow assembly of single spliceosomes in real time in whole cell extra...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086749/ https://ncbi.nlm.nih.gov/pubmed/21393538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1198830 |
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