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Synergistic assembly of human pre-spliceosomes across introns and exons

Most human genes contain multiple introns, necessitating mechanisms to effectively define exons and ensure their proper connection by spliceosomes. Human spliceosome assembly involves both cross-intron and cross-exon interactions, but how these work together is unclear. We examined in human nuclear...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Braun, Joerg E, Friedman, Larry J, Gelles, Jeff, Moore, Melissa J
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6035042/
https://ncbi.nlm.nih.gov/pubmed/29932423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37751
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