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Dot1 and Histone H3K79 Methylation in Natural Telomeric and HM Silencing
The expression of genes that reside near telomeres is attenuated through telomere position-effect variegation (TPEV). Using a URA3 reporter located at TEL-VIIL of S. cerevisiae, it was demonstrated that the disruptor of telomeric silencing-1 (Dot1) regulates TPEV by catalyzing the methylation of H3K...
Shranjeno v:
| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085244/ https://ncbi.nlm.nih.gov/pubmed/21474073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.006 |
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