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Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell cycle regulation of H3K79 dimethylation

To define the molecular regulators required for differential pattern of H3K79 methylation by Dot1, we performed a GPS screen and discovered that the components of the cell cycle-regulated SBF complex were required for normal levels of H3K79 di- but not trimethylation. Genome-wide mapping revealed th...

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Detalhes bibliográficos
Main Authors: Schulze, Julia M, Jackson, Jessica, Nakanishi, Shima, Gardner, Jennifer M, Hentrich, Thomas, Haug, Jeff, Johnston, Mark, Jaspersen, Sue L, Kobor, Michael S, Shilatifard, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222332/
https://ncbi.nlm.nih.gov/pubmed/19682934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.07.017
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